Practical guidance on the development of a non-cancer hazard range

Last Updated: 1 month ago Pfau, Thompson
Ed Pfau of Hull and Associates and Rod Thompson of Alliance for Site Closure

The method presented in the Case Study Summary (as undergoing review by the science panel) is the development of hazard ranges for non-cancer endpoints.  This method is one of several addressed in the full case study,  “Guidance for Contaminated Sites:  TCE risk assessment case study.”   Key aspects of the method for developing hazard ranges for the non-cancer endpoint (originally applied to TCE) have been refined for more general application to other chemicals in the Case Study Summary.  The file on “additional chemicals” illustrates the application of the method to chemicals that have not undergone the depth of mathematical analysis used in EPA’s TCE assessment.

Summary

Case Study

Appendix

Presentation by Rod Thompson

Presentation by Ed Pfau

 

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