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Perchlorate

Comparison of urinary iodine concentrations between the Chilean school age children and 6 to 11 year old children in the U.S.

 

Children in U.S. 1971-1974 (NHANES I1)

Children in U.S. 1988-1994 (NHANES III1)

Children in Chile2

Antofagasta (control)

Chanaral (low perchlorate exposure)

Taltal (high perchlorate exposure)

Sample size

1826

3058

53

49

60

Urine iodine (ug/dL)

55.6±3.6

(48.5-62.7)3

30.5±1.9

(26.8-34.2)

75.6±5.5

(64.5-86.7)

61.4±5.1

(51.1-71.7)

76.6±6.1

(64.4-88.8)

Urine iodine/creatinine (ug/g)

619.3±46.0

(529.1~709.5)

339.6±26.5

(287.7~391.5)

1057.2±51.9

(952.9~1161.5)

827.2±51.3

(724.0~930.4)

947.4±49.6

(848.2~1046.6)

All data are expressed as mean ± standard error (SE).

1.      The data for the children in U.S. are for the 6-11 years old age group reported from National Health and Nutrition Examination Surveys I (1971-1974) and III (1988-1994) (Hollowell et al., 1998)

2.      The data for the children in Chile are for the 6-8 years old age group reported by Crump et al. (2000).

3.      The values in the parentheses indicate 95% confidence interval. 

References:

Hollowell, J.G., Staehling, N.W., Hannon, W.H., Flanders, D.W., Gunter, E.W., Maberly, G.F., Braverman, L.E., Pino, S., Miller, D.T., Garbe, P.L., DeLozier, D.M., Jackson, R.J.. et al. (1998).  Iodine nutrition in the United States. Trends and public health implications: iodine excretion data from National Health and Nutrition Examination Surveys I and III (1971-1974 and 1988-1994). J Clin Endocrinol Metab. 83:3398-400. 

Crump, C., Michaud, P., Tellez, R., Reyes, C., Gonzalez, G., Montgomery, E. L., Crump, K. S., Lobo, G., Becerra, C., and Gibbs, J. P. (2000). Does perchlorate in drinking water affect thyroid function in newborns or school-age children? J. Occ. Environ. Med. 42, 603-612.

 

For further information, contact Ms. Joan Strawson at 910-692-7752 or Strawson@tera.org

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© 2003 Toxicology Excellence for Risk Assessment

2300 Montana Avenue, Suite 409, Cincinnati OH 45211
Phone: 513-542-7475
Fax: 513-542-7487
Email:
TERA@TERA.org


Last updated:  01/03/2007

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