Table 3.

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Table 3. LOEL and BMD of T4 and TSH Changes in Short-term
Animal Studies (relative human doses mg/kg-day).

Species	Study	Time point	LOEL	BMD10	BMD20
T4
Male
Rat	Caldwell et al. 1996	14 days	0.27	0.14	0.85
Rat	Siglin 1998	14 days	2.7	0.35	2.1
Female
Rat	Caldwell et al. 1996	14 days	0.027	0.016	0.17
Rat	Siglin 1998	14 days	2.7	0.45	4.3
Mouse	BRT-Burleson Res. Tech. Inc. 2000	14 days	---	---	---
Mouse	Keil et al. 1999	14 days	---	---	---
*TSH*
Male
Rat	Caldwell et al. 1996	14 days	0.27	0.090	0.16
Rat	Siglin 1998	14 days	0.053	0.0018	0.056
Female
Rat	Caldwell et al. 1996	14 days	0.12	0.012	0.064
Rat	Siglin 1998	14 days	0.013	0.00026	0.26
Mouse	BRT-Burleson Res. Tech. Inc. 2000	14 days	---	---	---
Mouse	Keil et al. 1999	14 days	---	---	---

Note: --- = Result is available but needs to be approved by the study authors.

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Phone: 513-542-7475
Fax: 513-542-7487
Email: TERA@TERA.org

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