What's new to ITER

May 8, 2008

• ATSDR published Toxicological Profiles for Ethylbenzene, Ethylene Glycol, and Styrene in September 2007.  The ITER entries for Ethylbenzene, Ethylene Glycol, and Styrene  have been updated based on the Toxicological Profiles. 

 March 31, 2008

• ATSDR published Draft for Public Comment Toxicological Profiles for Boron, Chlorine, and Plutonium in September 2007.  The ITER entries for Boron, Chlorine, and Plutonium have been updated based on the Toxicological Profiles. 

• ATSDR published updated Toxicological Profiles for Acrolein, Barium, Benzene, Lead, and Xylenes in August 2007.  The ITER entries for Acrolein, Barium, Benzene, Lead and Compounds, and Xylenes have been updated based on the Toxicological Profiles. 

• We recently added cancer classifications from IARC for Cyclohexanone, 2-Nitropropane, Propyleneimine (2-Methylaziridine), 1,1,1,2-Tetrachloroethane, 1,1,2,2-Tetrachloroethane, and  1,1,1-Trichloroethane.   The ITER entries for these chemicals are based on the IARC Monographs, and include a link to the Monographs.

January 14, 2008

• We recently added data from NSF International for Ethylene Diamine.  The ITER entry for this chemical is based on the NSF International Oral Risk Assessment Document, and includes a link to the Executive Summary of this document as well as a link to purchase the full report. 

December 18, 2007

• We recently added data from NSF International for Triethanolamine.  The ITER entry for this chemical is based on the NSF International Oral Risk Assessment Document, and includes a link to the Executive Summary of this document as well as a link to purchase the full report.  Triethanolamine is a new addition to ITER. 
• ATSDR published updated Toxicological Profiles for Arsenic and Heptachlor & Heptachlor Epoxide in August 2007.  The ITER entries for Arsenic, Cacodylic Acid (Dimethylarsinic Acid, DMA),  Heptachlor, Heptachlor Epoxide, Monomethylarsonic Acid (MMA), and Roxarsone  have been updated based on the Toxicological Profiles.  Monomethylarsonic Acid (MMA) and Roxarsone are new additions to ITER.
• ATSDR published an updated Toxicological Profile Dichlorobenzenes in August 2006.  The ITER entries for 1,2-Dichlorobenzene, 1,3-Dichlorobenzene, 1,4-Dichlorobenzene have been updated based on the Toxicological Profile.
• ATSDR published Toxicological Profiles for Hydrogen Sulfide, 1,1,1-Trichloroethane, Vinyl Chloride in July 2006.  The ITER entries for Hydrogen Sulfide, 1,1,1-Trichloroethane, Vinyl Chloride have been updated based on the Toxicological Profiles.

• U.S. EPA recently revised it data on IRIS for 1,1,1-Trichloroethane and 2,2,4-Trimethylpentane.  The ITER entries for 1,1,1-Trichloroethane and 2,2,4-Trimethylpentane have been updated based on IRIS, and include links to the IRIS website.

• We recently added data from NSF International for Acrolein, Acrylic Acid, Dibromoethane, 1,2- (Ethylene Dibromide), Dichloroacetic Acid, 1,3-Dichloropropene (Telone II), Methyl Ethyl Ketone (MEK), Methylmercury, 2-Methylnaphthalene, Phenol, Quinoline.  The ITER entry for these chemicals are based on information contained in the NSF International drinking water standards NSF/ANSI 60 and 61, as NSF International adopts the US EPA IRIS reference dose (RfD) for this chemical.

• We recently added the cancer classification from IARC for Dichloroacetic Acid.  The ITER entry for this chemical is based on the IARC Monograph, and includes a link to the Monograph.

• ATSDR published an updated Toxicological Profile for Pyrethrins and Pyrethroids in September 2003.  The ITER entries for Allethrin, Biphenthrin, Baythroid (Cyfluthrin), Cyhalothrin/karate, Cypermethrin, Danitol (Fenpropathrin), Deltamethrin, Fluvalinate, Permethrin, Pydrin (Esfenvalerate), Pyrethrins, Resmethrin, and Tralomethrin have been updated based on the Toxicological Profile. 

December 30, 2004

• We recently added data from NSF International for Acetone.  The ITER entry for this chemical is based on information contained in the NSF International drinking water standards NSF/ANSI 60 and 61, as NSF International adopts the US EPA IRIS reference dose (RfD) for this chemical.
• ATSDR published Draft for Public Comment Toxicological Profiles for 1,4-Dioxane, Hydrogen Sulfide, 1,1,1-Trichloroethane, and Vinyl Chloride in September 2004.  The ITER entries for 1,4-Dioxane, Hydrogen Sulfide, 1,1,1-Trichloroethane, and Vinyl Chloride have been updated based on the Toxicological Profiles. 
• ATSDR published an updated Toxicological Profile for Iodine in April 2004.  The ITER entries for Iodine, Potassium Iodide, Sodium Iodide have been updated based on the Toxicological Profile. 

November 29, 2004

• We recently added data from NSF International for Benzyl Alcohol, 4-Chloro-3-Methylphenol (p-Chloro-m-Cresol), di-tert-Butyl Peroxide, Furfural, Iodine, Methyl Isoamyl Ketone (MIAK), n-Butyl Acetate, and t-Butyl Alcohol (t-Butanol).  The ITER entries for these chemicals are based on the NSF International Oral Risk Assessment Documents, and include a link to the Executive Summaries of these documents as well as a link to purchase the full reports.  Benzyl Alcohol, 4-Chloro-3-Methylphenol (p-Chloro-m-Cresol), di-tert-Butyl Peroxide, Methyl Isoamyl Letone (MIAK), n-Butyl Acetate, and t-Butyl Alcohol (t-Butanol) are new additions to ITER.  

November 2, 2004

• We recently added data from NSF International for Gamma-Butyrolactone. The ITER entry for this chemical is based on the NSF International Oral Risk Assessment Document, and includes a link to the Executive Summary of this document as well as a link to purchase the full report.  Gamma-Butyrolactone is a new addition to ITER.  This is the first NSF International chemical to be made public on ITER.  More are on the way!

August 16, 2004

• U.S. EPA recently revised it data on IRIS for Boron and Compounds, 1,2-Dibromoethane, and Lead and Compounds.  The ITER entries for 1,2 Dibromoethane (Ethylene Dibromide), and Lead and compounds have been updated based on IRIS, and include a link to the IRIS website.

• We recently added cancer classifications from IARC for 1,2 Dibromoethane (Ethylene Dibromide), Ethyleneimine (Aziridine), and Lead and compounds.  The ITER entries for these chemicals are based on the IARC Monographs, and include a link to the Monographs.

July 26, 2004

• We recently added cancer classifications from IARC for 

  1,2-Dibromo-3-chloropropane (DBCP), 1,2-Dihydroxybenzene (Catechol),

  ortho Anisidine, and p-Chloroaniline (para-Chloroaniline).  The ITER entries for these chemicals are based on the IARC Monographs, and include a link to the Monographs.

May 21, 2004

• We recently added cancer classifications from IARC for Aldrin, Benzene, Bromodichloromethane, Dichloromethane (Methylene Chloride), and Mustard Gas (Sulfur Mustard).  The ITER entries for these chemicals are based on the IARC Monographs, and include a link to the Monographs.

• ATSDR published an updated Toxicological Profile for Sulfur Mustard (formerly called Mustard Gas) in September 2003.  The ITER entry for Mustard Gas (Sulfur Mustard) has been updated based on the Toxicological Profile. 

May 3, 2004

• ATSDR published an updated Toxicological Profiles for Atrazine, Malathion, and Selenium in September 2003.  The ITER entries for Atrazine, Malathion, and Selenium and Compounds have been updated based on the Toxicological Profiles. 

April 21, 2004

• See our press release on exciting news about the International Toxicity Estimates for Risk (ITER) Database

April 19, 2004 

      ITER IS ALSO AVAILABLE ON TOXNET!

• ITER has been added to the National Library of Medicine's (NLM) TOXNET system, (http://toxnet.nlm.nih.gov).  As part of TOXNET, ITER can now be searched by chemical synonym and via free text.  In addition, a multi-file searching function will soon be added and will allow a single query to be run against multiple toxicological databases, including ITER.  Links to TOXLINE will allow users to obtain current literature references and abstracts on ITER chemicals.  Please note that ITER is now available in both its original location on TERA's website (www.tera.org/iter) as well as on the TOXNET system (http://toxnet.nlm.nih.gov).  Both locations contain the same data, however, the TOXNET system has enhanced search capabilities.

      NEW ORGANIZATIONS BEING ADDED! 

• We are in the process of adding oral risk data to ITER from NSF International, an independent, not-for-profit global leader in providing public health and safety risk management solutions.  In the meantime, more information about NSF International can be obtained at http://www.nsf.org.

• We are in the process of adding cancer classifications to ITER from the International Agency for Research on Cancer's (IARC) Monographs. In the meantime, cancer classifications from IARC can be obtained online directly from the IARC Monographs at http://monographs.iarc.fr/.  We recently added cancer classifications from IARC for Cadmium and Arsenic.  The ITER entries for these chemicals are based on the IARC Monographs, and include a link to the Monographs

January 28, 2004

• U.S. EPA recently added data to IRIS for 2-Methylnaphthalene.  The ITER entry for 2-Methylnaphthalene has been updated based on IRIS, and include a link to the IRIS website.

December 22, 2003

• We recently added data from RIVM (The Netherlands) for Calcium Cyanide, Copper Cyanide, Hydrogen Cyanide, Potassium Cyanide, Silver Cyanide, and Sodium Cyanide.  The ITER entries for these chemicals are based on the RIVM report, “Re-evaluation of  human-toxicological maximum permissible risk levels” (2001), and include a link to this report.
  

• We recently added data from ATSDR to Calcium Cyanide, Copper Cyanide, Cyanogen, Cyanogen Chloride (Chlorine Cyanide), Potassium Cyanide, and Potassium Silver Cyanide.   The ITER entry for each of these chemicals has been created based on the Toxicological Profile for Cyanide.
  

• We also made minor format edits to Cyanide, free and Cyanogen bromide.

November 28, 2003

• We recently added data from RIVM (The Netherlands) for 1,2-Dihydroxybenzene (Catechol), 1,3-Dihydroxybenzene (Resorcinol), 1,4-Dihydroxybenzene (Hydroquinone),  Acenaphthene,  Acenaphthylene, Anthracene, Automotive Gasoline (Petrol), Benz[a]anthracene, Benzo[a]pyrene,  Benzo[b]fluoranthene,  Benzo[g,h,i]perylene,  Benzo[k]fluoranthene,  Benzo[j]fluoranthene, Chromium(III), chromic ion, Chromium(VI), hexavalent, Chrysene, Cyclohexanone, Dibenz[a,h]anthracene, Dihydroxybenzene, Fluoranthene, Fluorene, Mercuric chloride (mercury, inorganic), Indeno[1,2,3-cd]pyrene, Mercury, elemental, Methylmercury, 3-Methylphenol (m-cresol), 2-Methylphenol (o-cresol), 4-Methylphenol (p-cresol), Naphthalene, Phenanthrene, Pyrene, Pyridine, Tetrahydrothiophene.  The ITER entries for these chemicals are based on the RIVM report, “Re-evaluation of human-toxicological maximum permissible risk levels” (2001), and include a link to this report.  1,2-Dihydroxybenzene (Catechol), 1,3-Dihydroxybenzene (Resorcinol), Dihydroxybenzene, Fluorene, and Tetrahydrothiophene are new additions to ITER.

November 18, 2003

• We recently changed the CAS number for soluble Fluoride (Fluorine) from "fluoride" (no CAS) to "7782-41-4". 
  

• ATSDR published Draft for Public Comment Toxicological Profiles for Bromoform & Chlorodibromomethane, Carbon Tetrachloride, Hexachlorocyclohexanes, Naphthalene, 1-Methylnaphthalene & 2-Methylnaphthalene, Tin, Tungsten, and Zinc in September 2003.  The ITER entries for alpha-Hexachlorocyclohexane, beta-Hexachlorocyclohexane, Bromoform, Carbon Tetrachloride, delta-Hexachlorocyclohexane, Dibromochloromethane (Chlorodibromomethane), Dibutyltin Dichloride, epsilon-Hexachlorocyclohexane, gamma-Hexachlorocyclohexane, Inorganic Tin, 1-Methylnaphthalene, 2-Methylnaphthalene, Naphthalene, technical- Hexachlorocyclohexane, Tributyltin Oxide, Tungsten, Zinc, have been updated based on the Toxicological Profiles.  Dibutyltin Dichloride, 1-Methylnaphthalene, 2-Methylnaphthalene, and Tungsten are new additions to ITER.
  

• We made minor format edits to 2-(2-methyl-4-chlorophenoxy)propionic acid, 4-(2-methyl-4-chlorophenoxy)butyric acid, and Zinc cyanide,

• We recently updated the links for Health Canada's PSL1 substances on ITER.  The ITER entries for these chemicals now link to the Health Canada website at http://www.hc-sc.gc.ca/hecs-sesc/exsd/psl1.htm.

• We recently added data from RIVM (The Netherlands) for Benzene, Chlorobenzene,  1,2-Dichlorobenzene, 1,3-Dichlorobenzene, cis-1,2-Dichloroethylene,  trans-1,2-Dichloroethylene, 1,2,3-Trichlorobenzene, 1,2,4-Trichlorobenzene, Trichloroethylene (TCE), and Xylenes.  The ITER entries for these chemicals are based on the RIVM report, “Re-evaluation of human-toxicological maximum permissible risk levels” (2001), and include a link to this report. 
  
• ATSDR published updated Toxicological Profiles for DDT, DDE, and DDD in September 2002, and for Benzidine in September 2001.  The ITER entries for Benzidine, DDT,  DDD, and DDE have been updated based on the Toxicological Profiles.

• ATSDR published updated Toxicological Profiles for Bis(2-ethylhexyl)Phthalate (DEHP) and Hexachlorobenzene in September 2002.  The ITER entries for Bis(2-ethylhexyl)Phthalate  and Hexachlorobenzene  have been updated based on the Toxicological Profiles.

• U.S. EPA recently revised its data on IRIS for Methyl Isobutyl Ketone (MIBK). The ITER entry for Methyl Isobutyl Ketone (MIBK) has been updated based on IRIS, and includes a link to the IRIS website.
• We recently added data from RIVM (The Netherlands) for Cadmium and 1,4-Dichlorobenzene.   The ITER entries for these chemicals are based on the RIVM report, “Re-evaluation of human-toxicological maximum permissible risk levels” (2001), and include a link to this report. 
• ATSDR published updated Toxicological Profiles for Aldrin/Dieldrin, Creosote, and Methoxychlor in September 2002.  The ITER entries for Aldrin, Coke Oven Emissions, Coal Tar, Creosote,  Dieldrin, and Methoxychlor have been updated based on the Toxicological Profiles.
• We recently added data from ATSDR for 1, 4-Dichlorobenzene.  The ITER entry for this chemical has been created based on the Toxicological Profile for 1,4-Dichlorobenzene. 

• U.S. EPA recently revised its data on IRIS for Benzene, Diesel Engine Emissions, and Xylenes. The ITER entries for Benzene, Diesel Engine Emissions, and Xylenes have been updated based on IRIS, and include a link to the IRIS website.
• We recently added data from ATSDR for Bromodichloromethane.  The ITER entry for this chemical has been created based on the Toxicological Profile.
• We recently updated the links for Health Canada's PSL2 substances on ITER.  The ITER entries for these chemicals now link to the Health Canada website at http://www.hc-sc.gc.ca/hecs-sesc/exsd/psl2.htm.