July 30, 2010

 

We recently added cancer classifications from IARC for 1,3-Butadiene,  Ethylene Oxide, Vinyl Bromide,  Vinyl Chloride, and Vinyl Fluoride.   The ITER entries for these chemicals are based on Volume 97 of the IARC Monographs, and include a link to the Monographs.  Vinyl Fluoride is a new addition to ITER.

 

We recently added cancer classifications from IARC for:

• Acetaldehyde

• Acrylamide

• Antimony Trioxide

• Aramite

• Asbestos

• Atrazine

• Bromoform

• Caprolactam

• Carbon Tetrachloride

• Chloroform (Trichloromethane)

• Chloral Hydrate

• Cobalt

• Deltamethrin

• Di(2-ethylhexyl)adipate

• 1,4-Dichlorobenzene

• 1,2-Dichloroethane

• 1,2-Dichloropropane

• 1,2-Epoxybutane

• Ethylene Thiourea

• Formaldehyde

• Furan

• Glycidaldehyde

• Hexachlorobenzene

• Hexachloroethane

• Hydrazine

• 4,4'-Methylenebis(2-chloroaniline) (MBOCA)

• Methylene diphenyl diisocyanate

• Trichloroacetic Acid

• 1,2,3-Trichloropropane

• Trifluralin

• 2,4,6-Trinitrotoluene

• 1,1-Dichloroethylene (Vinylidene Chloride)

 

The ITER entries for these chemicals are based on the IARC Monographs, and include a link to the Monographs. 

 

 

June 15, 2010

 

We recently added inhalation risk data from the Texas Commission on Environmental Quality (TCEQ) for 1,3-Butadiene.   TCEQ’s data is located in the ITER PR (Peer Review) column for this chemical, and is based on TCEQ’s Development Support Document (DSD) for 1,3- Butadiene.  (TERA conducted an independent peer review of this assessment). 

 

 

May 27, 2010

 

U.S. EPA recently revised it data on IRIS for Acrylamide, Carbon Tetrachloride, and Ethylene glycol monobutyl ether (EGBE).  The ITER entries for Acrylamide,  Carbon Tetrachloride, and  2-Butoxyethanol (EGBE)  have been updated based on IRIS, and include links to the IRIS website.

 

We recently updated data from NSF International for 2-Butoxyethanol (EGBE) . The ITER entry for this chemical is based on information contained in the NSF International drinking water standards NSF/ANSI 60 and 61, as NSF International adopts the US EPA IRIS reference dose (RfD) for these chemicals.

 

March 10, 2010

 

We recently added data from NSF International for 2,6-Dichloro-1,4-Benzenediamine and 4,4’-Methylenedianiline.  The ITER entries for these chemicals are based on the NSF International Oral Risk Assessment Documents, and include a link to the Executive Summary of the documents as well as a link to purchase the full reports.

 

U.S. EPA recently revised it data on IRIS for Thallium, Thallium Oxide, and Thallium Selenite.  The ITER entries for Thallium,  Thallium Oxide (formerly called Thallic Oxide), and Thallium Selenite have been updated based on IRIS, and include links to the IRIS website. The Thallium assessment replaces the assessments for the following related substances (which have subsequently been removed from ITER as well):

 

Thallium acetate

• Thallium carbonate

• Thallium chloride

• Thallium nitrate

• Thallium (I) sulfate

 

ATSDR published a Draft for Public Comment Toxicological Profile for Phosphate Ester Flame Retardants in September 2009. The ITER entries for Tributoxyethyl phosphate (TBEP), Tri-(2-chloroethyl) phosphate (TCEP), Tributyl phosphate (TnBP), Tris(1,3-dichloro-2-propyl) phosphate (TDCP), Triisobutyl phosphate (TiBP), Triphenyl phosphate (TPP), Tri-(2-chloroisopropyl) phosphate (TCPP), have been added based on the Toxicological Profiles.  All seven of these chemicals are new additions to ITER.

 

ATSDR published a Draft for Public Comment Toxicological Profile for Perfluoroalkyls in May 2009. The ITER entry for Perfluoroalkyls has been added based on the Toxicological Profile.  Perfluoroalkyls is a new addition to ITER.

 

December 31, 2009

 

U.S. EPA recently added new data to IRIS for Bromobenzene, Cerium Oxide and Cerium Compounds, and Chlordecone (Kepone).  The ITER entries for Bromobenzene, Cerium Oxide and Cerium Compounds, and Chlordecone (Kepone) have been added based on IRIS, and include a link to the IRIS website.  Bromobenzene and Cerium Oxide and Cerium Compounds are new additions to ITER.  

U.S. EPA recently revised its data on IRIS for 2-Hexanone and 1,2,3-Trichloropropane. The ITER entries for 2-Hexanone and 1,2,3-Trichloropropane have been updated based on IRIS, and includes links to the IRIS website.  

ATSDR published Draft for Public Comment Toxicological Profiles for Acrylamide, 1,3-Butadiene, Carbon Monoxide, and Vanadium in September 2009. The ITER entries for Acrylamide, 1,3-Butadiene,  Carbon Monoxide, Vanadium, and Vanadium Pentoxide have been updated based on the Toxicological Profiles.  Carbon Monoxide is a new addition to ITER.

 

March 30, 2009

ATSDR published Draft for Public Comment Toxicological Profiles for Cadmium, Chromium, and Manganese in September 2008. The ITER entries for Cadmium, Chromium (III), chromic ion, Chromium (VI), hexavalent, and Manganese  have been updated based on the Toxicological Profiles.

 

ATSDR published updated Toxicological Profiles for Aluminum, Cresols, Diazinon, Dichloropropenes, Guthion, Perchlorates, Phenol, and 1,1,2,2-Tetrachloroethane in September 2008. The ITER entries for Aluminum, Ammonium Perchlorate,  Diazinon, 1,1-Dichloropropene, 1,2-Dichloropropene,  1,3-Dichloropropene (Telone II), 2,3- Dichloropropene, 3,3-Dichloropropene,  Guthion, 2-Methylphenol (o-cresol), 3-Methylphenol (m-cresol), 4-Methylphenol (p-cresol), Phenol, 1,1,2,2-Tetrachloroethane, and Tricresol have been updated based on the Toxicological Profiles.  1,1-Dichloropropene, 1,2-Dichloropropene,  2,3- Dichloropropene, and 3,3-Dichloropropene are new additions to ITER.

 

February 12, 2009

 

We recently added data from NSF International for Diethanolamine,  2-Ethylhexanoic Acid, and  2-Ethylhexanol.   The ITER entries for these chemicals are based on the NSF International Oral Risk Assessment Documents, and include a link to the Executive Summary of these documents as well as a link to purchase the full report. Diethanolamine, 2-Ethylhexanoic Acid, and 2-Ethylhexanol are new additions to ITER.

 

U.S. EPA recently added new data to IRIS for Propionaldehyde.  The ITER entry for Propionaldehyde has been added based on IRIS, and includes a link to the IRIS website.  Propionaldehyde is a new addition to ITER.

 

U.S. EPA recently revised it data on IRIS for Nitrobenzene. The ITER entry for Nitrobenzene has been updated based on IRIS, and includes links to the IRIS website.

 

December 11, 2008

 

We recently added data from NSF International for Ethanolamine.    The ITER entry for this chemical is based on the NSF International Oral Risk Assessment Document, and includes a link to the Executive Summary of this document as well as a link to purchase the full report.

 

ATSDR published a Draft for Public Comment Toxicological Profile for Radon in September 2008. The ITER entry for Radon  has been updated based on the Toxicological Profile.

 

September 8, 2008

We recently launched a new database that is a companion to ITER called the Risk Information Exchange (RiskIE). Explore RiskIE at http://www.allianceforrisk.org/RiskIE.htm.  

 

We recently published a manuscript about our ITER and RiskIE (Risk Information Exchange) databases:  Wullenweber, A., et al.  2008.  Resources for global risk assessment: The International Toxicity Estimates for Risk (ITER) and Risk Information Exchange (RiskIE) databases.  Toxicol. Appl. Pharmacol.  doi:10.1016/j.taap.2007.12.035

 

U.S. EPA recently added new data to IRIS for 2,2’,4,4’,5,5’-Hexabromodiphenyl Ether (BDE-153), 2,2',4,4',5-Pentabromodiphenyl Ether (BDE-99), and 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47).  ITER entries for 2',4,4',5,5'- Hexabromodiphenyl ether (BDE-153),  2,2',4,4',5-Pentabromodiphenyl Ether (BDE-99), and  2,2',4,4'-Tetrabromodiphenyl ether (BDE-47)  have been added based on IRIS, and include links to the IRIS website.  2,2’,4,4’,5,5’-Hexabromodiphenyl Ether (BDE-153), 2,2',4,4',5-Pentabromodiphenyl Ether (BDE-99), and 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) are new additions to ITER.

 

U.S. EPA recently revised it data on IRIS for Decabromodiphenyl Ether (DecaBDE).  The ITER entry for Decabromodiphenyl Ether (DecaBDE)  has been updated based on IRIS, and include links to the IRIS website.

 

ATSDR published updated an updated Toxicological Profile for Cyanide in July 2006.  The ITER entries for Calcium Cyanide, Copper Cyanide, Cyanide, free,  Cyanogen, Cyanogen Chloride (Chlorine Cyanide), Hydrogen Cyanide, Potassium Cyanide, Potassium Silver Cyanide, Sodium Cyanide, and Zinc Cyanide have been updated based on the Toxicological Profile.

 

May 8, 2008

 

ATSDR published Toxicological Profiles for Ethylbenzene, Ethylene Glycol, and Styrene in September 2007.  The ITER entries for Ethylbenzene, Ethylene Glycol, and Styrene  have been updated based on the Toxicological Profiles. 

 

March 31, 2008

 

ATSDR published Draft for Public Comment Toxicological Profiles for Boron, Chlorine, and Plutonium in September 2007.  The ITER entries for Boron, Chlorine, and Plutonium have been updated based on the Toxicological Profiles. 

 

ATSDR published updated Toxicological Profiles for Acrolein, Barium, Benzene, Lead, and Xylenes in August 2007.  The ITER entries for Acrolein, Barium, Benzene, Lead and Compounds, and Xyleneshave been updated based on the Toxicological Profiles. 

 

We recently added cancer classifications from IARC for Cyclohexanone, 2-Nitropropane, Propyleneimine (2-Methylaziridine), 1,1,1,2-Tetrachloroethane, 1,1,2,2-Tetrachloroethane, and  1,1,1-Trichloroethane.   The ITER entries for these chemicals are based on the IARC Monographs, and include a link to the Monographs.

 

January 14, 2008

 

We recently added data from NSF International for Ethylene Diamine.  The ITER entry for this chemical is based on the NSF International Oral Risk Assessment Document, and includes a link to the Executive Summary of this document as well as a link to purchase the full report. 

 

December 18, 2007

 

We recently added data from NSF International for Triethanolamine.  The ITER entry for this chemical is based on the NSF International Oral Risk Assessment Document, and includes a link to the Executive Summary of this document as well as a link to purchase the full report.  Triethanolamine is a new addition to ITER. 

 

ATSDR published updated Toxicological Profiles for Arsenic and Heptachlor & Heptachlor Epoxide in August 2007.  The ITER entries for Arsenic, Cacodylic Acid (Dimethylarsinic Acid, DMA),  Heptachlor, Heptachlor Epoxide, Monomethylarsonic Acid (MMA), and Roxarsone  have been updated based on the Toxicological Profiles.  Monomethylarsonic Acid (MMA) and Roxarsone are new additions to ITER.

 

ATSDR published an updated Toxicological Profile Dichlorobenzenes in August 2006.  The ITER entries for 1,2-Dichlorobenzene, 1,3-Dichlorobenzene, 1,4-Dichlorobenzene have been updated based on the Toxicological Profile.

 

ATSDR published Toxicological Profiles for Hydrogen Sulfide, 1,1,1-Trichloroethane, Vinyl Chloride in July 2006.  The ITER entries for Hydrogen Sulfide, 1,1,1-Trichloroethane, Vinyl Chloride have been updated based on the Toxicological Profiles.

 

October 12, 2007

 

U.S. EPA recently revised it data on IRIS for 1,1,1-Trichloroethane and 2,2,4-Trimethylpentane.  The ITER entries for 1,1,1-Trichloroethane and 2,2,4-Trimethylpentane have been updated based on IRIS, and include links to the IRIS website.

 

May 25, 2007

 

ATSDR published an updated Toxicological Profile for 1,4-Dioxane in April 2007.  The ITER entry for 1,4 – Dioxane  has been updated based on the Toxicological Profile.

 

April 26, 2007

 

We recently added data from the US Army Center for Health Promotion and Preventive Medicine (CHPPM) for six chemical warfare agents: Lewisite,  Sarin (GB),  Soman (GD),  Sulfur Mustard (HD),  Tabun (GA), and VX.   This data underwent peer review by the National Research Council (NRC), and is located under the IPRV column on ITER.  Lewisite, Sarin (GB), Soman (GD), Tabun (GA), and VX are new additions to ITER.

 

April 12, 2007

     

NEW COLUMN ADDED! 

 

We recently added a new column to ITER, entitled “IPRV – Independently Peer Reviewed Values”.  The IPRV column contains data from those organizations that do not meet the criteria for having their own column (such as having data for at least 40 chemicals) and whose risk values have undergone peer review outside TERA’s ITER Peer Review process.  In addition, we changed the existing column name “ITER” to “ITER PR”.  The ITER PR column contains data from those organizations whose risk values have undergone peer review through TERA’s ITER Peer Review process (http://www.tera.org/peer).  This independent peer review is convened by TERA through its Peer Review Program, and if the expert panel concurs with an assessment, it can be made available to the public on the ITER database.  These independent values can only be found on ITER.